Are physical activity, sleep, and joint pain associated with physical function and quality of life in individuals with multimorbidity? A cross-sectional analysis of the MOBILIZE trial

Abstract

Purpose: This study investigated the associations between physical activity, sleep, and joint pain intensity with physical function and health-related quality of life (HrQoL) in people with multimorbidity. Methods: A pre-specified cross-sectional study using baseline data from participants with multimorbidity in the MOBILZE trial. Outcomes were physical function (6-minute walk test) and HrQoL (EQ-5D-5 L). Exposures were device-measured physical activity (min/week), joint pain intensity (0-100 visual analogue scale), device-measured sleep efficiency (%), and sleep quality (Modified Karolinska Sleep Questionnaire, 0–5 Likert scale). Separate and combined linear regression models were used to a..